The knowledge of DNA sequences, of the genome of organisms has become inevitable for basic research. The increased availability of high quality genome sequences for various species offer new opportunities for studying genetic and structural variations like, Single Nucleotide Polymorphism (SNPs), Copy Number Variations (CNVs), insertions, deletions, gene ontology, pathway analysis and other genome wide association studies (GWAS) that can affect gene regulatory pathways and signalling networks.
Elango Genetics provides both de-novo and reference based sequencing using multiple set of libraries like Paired End and Mate Paired libraries using various NGS technologies.
We provide Whole Genome Sequencing services on various platforms like Illumina HiSeq 2000/2500, NextSeq500, MiSeq, Roche GS FLX+ and PacBio including project scope, technology selection, data requirements, data generation to high quality draft genome assembly and submission support. We have developed expertise in generation of quality data for animals, plants, bacteria, virus, fungus and mitochondrial genomes.
Exome sequencing, involves sequencing of transcribed region within the DNA by capturing the exonic sequence alone. The human exome encompasses approximately 1% of sequence of the complete genome and exome sequencing costs are approximately 10% of whole genome sequencing costs. Exome sequencing has been extensively used to deliver novel mutation in many diseases including cancer, diabetes Thalassemia, cystic fibrosis, cardiovascular disorders and Alzheimer disease.
Elango Genetics empowers you to identify variations in individual DNA sequence and mapped back to the individual medical concerns in an effort to discover the cause of the medical disorder by providing the best solutions for human exome sequencing services.
Whole transcriptome sequencing involves cDNA library preparation followed by sequencing of entire RNA pool that is present within one given cell. Thus, empowering you to profile the whole population of mRNA and enabling mapping and digital quantification of whole transcriptome. We have successfully established accurate and comprehensive methodologies for animal, plants, bacteria, fungi and many more.
Metagenomics is the study of microbial communities sampled directly from their natural environment. This enables analysis of populations including many uncultivable and often unknown microbes. We also provide metagenomics analysis for the organisms/species apart from microbial flora.
Currently, Metagenomics studies are facilitated by the rapid development of NGS techniques, which is faster and cost effective method of metagenomics studies.